Cardiovascular & Respiratory Pathology · NEET PG Preparation Pathology
A 45-year-old male with a history of untreated streptococcal pharyngitis several weeks ago presents with migratory polyarthritis, subcutaneous nodule…
Practice question from Cardiovascular & Respiratory Pathology (NEET PG Preparation Pathology), with the correct answer and a step-by-step solution.
medium · MCQ · Q-67A5DB
A 45-year-old male with a history of untreated streptococcal pharyngitis several weeks ago presents with migratory polyarthritis, subcutaneous nodules, and a new-summit systolic murmur. Endocardial biopsy demonstrates characteristic focal inflammatory lesions consisting of a zone of fibrinoid necrosis surrounded by lymphocytes, plasma cells, and plump macrophages with abundant basophilic cytoplasm. What is the classic name for these macrophages?
- A.Langhans giant cells
- B.Aschoff cells
- C.Schaumann bodies
- D.Anitschkow cellsCorrect answer
Solution
Aschoff bodies are the pathognomonic granulomatous lesions of rheumatic fever found in the heart. The characteristic modified macrophages with abundant cytoplasm and central chromatin condensed into a wavy, caterpillar-like ribbon are called Anitschkow cells.
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