Cardiovascular & Respiratory Pathology · NEET PG Preparation Pathology

A 60-year-old chronic smoker presents with a centrally located right lung mass. Biopsy reveals nests of malignant epithelial cells showing intercellu…

Practice question from Cardiovascular & Respiratory Pathology (NEET PG Preparation Pathology), with the correct answer and a step-by-step solution.

medium · MCQ · Q-EFDF0D

A 60-year-old chronic smoker presents with a centrally located right lung mass. Biopsy reveals nests of malignant epithelial cells showing intercellular bridges and keratinization, along with areas of keratin pearls. Which of the following is the most likely diagnosis?

  1. A.Small cell carcinoma
  2. B.Adenocarcinoma
  3. C.Squamous cell carcinomaCorrect answer
  4. D.Large cell carcinoma

Solution

Squamous cell carcinoma of the lung is typically centrally located and strongly associated with smoking. Histologically, it is characterized by squamous differentiation, including intercellular bridges and keratin pearls.

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