Cardiovascular & Respiratory Pathology · NEET PG Preparation Pathology

A 55-year-old male with a history of anterior wall myocardial infarction 3 days ago develops sudden, severe chest pain, profound hypotension, and a d…

Practice question from Cardiovascular & Respiratory Pathology (NEET PG Preparation Pathology), with the correct answer and a step-by-step solution.

medium · MCQ · Q-8804F7

A 55-year-old male with a history of anterior wall myocardial infarction 3 days ago develops sudden, severe chest pain, profound hypotension, and a disappearance of carotid pulses despite continuing electrical activity on the cardiac monitor. Which of the following is the most likely underlying structural complication?

  1. A.Ventricular septal rupture
  2. B.Free wall myocardial rupture with cardiac tamponadeCorrect answer
  3. C.Papillary muscle rupture with acute mitral regurgitation
  4. D.Left ventricular pseudoaneurysm formation

Solution

Free wall rupture typically occurs within 3 to 7 days post-myocardial infarction when the necrotic myocardium is weakest due to maximal neutrophil infiltration and enzymatic lysis. It leads to rapid hemopericardium, cardiac tamponade, and electromechanical dissociation (pulseless electrical activity).

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