Paediatric Cardiology & Nephrology · NEET PG Preparation Paediatrics
An 8-year-old girl is brought to the emergency department with gross hematuria, facial puffiness, and mild hypertension 12 days after recovering from…
Practice question from Paediatric Cardiology & Nephrology (NEET PG Preparation Paediatrics), with the correct answer and a step-by-step solution.
medium · MCQ · Q-82A50D
An 8-year-old girl is brought to the emergency department with gross hematuria, facial puffiness, and mild hypertension 12 days after recovering from a skin infection. Laboratory tests reveal elevated anti-streptolysin O (ASO) titers and low serum C3 complement levels. Which of the following is the hallmark electron microscopic finding in renal biopsy of this condition?
- A.Podocyte foot process effacement only
- B.Subepithelial humpsCorrect answer
- C.Subendothelial deposits
- D.Basal lamina splitting ('basket-weave' appearance)
Solution
Post-streptococcal glomerulonephritis (PSGN) typically presents with nephritic syndrome following a streptococcal infection. The classic electron-dense microscopic finding is 'hump-shaped' subepithelial immune complex deposits (subepithelial humps).
More from Paediatric Cardiology & Nephrology
- A 3-year-old child presents with recurrent upper respiratory tract infections and a continuous machinery murmur best heard at the left uppe…
- A 5-year-old boy presents with periorbital edema, generalized swelling, and frothy urine for the last 5 days. Laboratory investigations rev…
- A newborn infant presents with severe cyanosis and respiratory distress shortly after birth, which does not improve significantly with admi…
- A 4-year-old child with Tetralogy of Fallot suddenly becomes extremely cyanotic, agitated, and hyperpneic while crying, followed by limpnes…
Practise more Paediatrics
Sign up free for adaptive practice on this chapter, with instant feedback and hints on every question.
Start practising freeFree to start · No credit card needed