Paediatric Cardiology & Nephrology · NEET PG Preparation Paediatrics
A 3-year-old child presents with recurrent upper respiratory tract infections and a continuous machinery murmur best heard at the left upper sternal…
Practice question from Paediatric Cardiology & Nephrology (NEET PG Preparation Paediatrics), with the correct answer and a step-by-step solution.
easy · MCQ · Q-F0758C
A 3-year-old child presents with recurrent upper respiratory tract infections and a continuous machinery murmur best heard at the left upper sternal border. Femoral pulses are bounding, and wide pulse pressure is noted. Which of the following is the most appropriate initial pharmacological agent for closure of this lesion if the child was a premature neonate?
- A.Prostaglandin E1
- B.IndomethacinCorrect answer
- C.Furosemide
- D.Digoxin
Solution
The clinical presentation is classic for a Patent Ductus Arteriosus (PDA) with a continuous machinery murmur and bounding pulses. Indomethacin (or ibuprofen), which are cyclooxygenase inhibitors, are used for pharmacological closure of a PDA, particularly in premature neonates. Prostaglandin E1 is used to keep the ductus open, not closed.
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