General Pharmacology · NEET PG Preparation Pharmacology
A drug is administered as a continuous intravenous infusion. If the elimination half-life of this drug is 4 hours, approximately how long will it tak…
Practice question from General Pharmacology (NEET PG Preparation Pharmacology), with the correct answer and a step-by-step solution.
hard · MCQ · Q-BB1754
A drug is administered as a continuous intravenous infusion. If the elimination half-life of this drug is 4 hours, approximately how long will it take to reach 90% of its ultimate steady-state plasma concentration?
- A.4 hours
- B.8 hours
- C.13.3 hoursCorrect answer
- D.20 hours
Solution
Steady-state achievement during continuous infusion depends on half-lives. 1 half-life = 50%, 2 = 75%, 3 = 87.5%, and 3.3 half-lives = 90% (calculated via , which gives ). With a half-life of 4 hours, hours.
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