Neurosurgery & Cardiothoracic Surgery · NEET PG Preparation Surgery

A 45-year-old woman presents with progressive bitemporal hemianopia and amenorrhea-galactorrhea. Serum prolactin levels are markedly elevated at 4,50…

Practice question from Neurosurgery & Cardiothoracic Surgery (NEET PG Preparation Surgery), with the correct answer and a step-by-step solution.

easy · MCQ · Q-02408B

A 45-year-old woman presents with progressive bitemporal hemianopia and amenorrhea-galactorrhea. Serum prolactin levels are markedly elevated at 4,500 ng/mL. Which of the following is the initial treatment of choice?

  1. A.Transsphenoidal surgical resection
  2. B.Dopamine agonist therapy (e.g., cabergoline)Correct answer
  3. C.Fractionated stereotactic radiotherapy
  4. D.Observation with serial visual field testing

Solution

Unlike most other pituitary adenomas where surgery is the primary treatment, prolactinomas are treated medically as the first-line therapy. Dopamine agonists such as cabergoline or bromocriptine effectively lower prolactin levels and reduce tumor size, even in the presence of mass effect and visual symptoms.

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