Neurosurgery & Cardiothoracic Surgery · NEET PG Preparation Surgery

A 54-year-old man presents with progressive headache, personality changes, and right-sided hemiparesis. MRI reveals a butterfly-like enhancing mass i…

Practice question from Neurosurgery & Cardiothoracic Surgery (NEET PG Preparation Surgery), with the correct answer and a step-by-step solution.

medium · MCQ · Q-89AE51

A 54-year-old man presents with progressive headache, personality changes, and right-sided hemiparesis. MRI reveals a butterfly-like enhancing mass in the corpus callosum with extensive surrounding edema and central necrosis. Which of the following is the most likely pathological diagnosis?

  1. A.Meningioma
  2. B.Glioblastoma multiformeCorrect answer
  3. C.Primary CNS lymphoma
  4. D.Schwannoma

Solution

Glioblastoma multiforme (GBM) is the most malignant astrocytic tumor (WHO Grade IV) and characteristically crosses the corpus callosum, presenting as a 'butterfly' glioma. It typically shows central necrosis, microvascular proliferation, and surrounding edema.

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