Blood & Immunity · NEET PG Preparation Physiology
During the process of hemostasis, von Willebrand factor (vWF) plays a critical role in primary hemostasis. What is the primary function of vWF?
Practice question from Blood & Immunity (NEET PG Preparation Physiology), with the correct answer and a step-by-step solution.
easy · MCQ · Q-0FAF9A
During the process of hemostasis, von Willebrand factor (vWF) plays a critical role in primary hemostasis. What is the primary function of vWF?
- A.Activation of factor XIII to stabilize fibrin polymers
- B.Mediating platelet adhesion to exposed subendothelial collagenCorrect answer
- C.Conversion of fibrinogen to fibrin monomers
- D.Inhibition of plasminogen activation
Solution
von Willebrand factor (vWF) acts as a bridge between exposed subendothelial collagen and the glycoprotein Ib (GPIb) receptor on the platelet membrane, facilitating platelet adhesion, which is the first step in primary hemostasis.
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