A 35-year-old male with a history of recurrent nephrolithiasis and hypertension is prescribed a medication that decreases intraocular pressure and is…

Acetazolamide is a carbonic anhydrase inhibitor that reduces aqueous humor production, lowering intraocular pressure. It also causes metabolic acidosis by increasing bicarbonate excretion in the urine, which in turn enhances tubular calcium reabsorption and decreases urinary citrate excretion, paradoxically predisposing to calcium phosphate stones, but in some contexts, it's a classic example of autonomic/ophthalmic/metabolic drug cross-effects. Wait, acetazolamide is a carbonic anhydrase inhibitor, not strictly an ANS drug. Let's use a pure ANS drug instead to strictly fit the topic.