Autonomic Nervous System Drugs · NEET PG Preparation Pharmacology

A 60-year-old man is brought to the emergency department with acute onset of severe eye pain, blurred vision, and seeing halos around lights. Examina…

Practice question from Autonomic Nervous System Drugs (NEET PG Preparation Pharmacology), with the correct answer and a step-by-step solution.

easy · MCQ · Q-C1FA0F

A 60-year-old man is brought to the emergency department with acute onset of severe eye pain, blurred vision, and seeing halos around lights. Examination reveals a fixed, mid-dilated pupil and a stony-hard eye. Which of the following classes of drugs is strictly contraindicated in this patient due to the risk of worsening the condition?

  1. A.Direct-acting cholinergic agonists
  2. B.Carbonic anhydrase inhibitors
  3. C.Mydriatic and cycloplegic agentsCorrect answer
  4. D.Beta-adrenergic blockers

Solution

The clinical presentation is classic for acute angle-closure glaucoma. Mydriatic (pupil-dilating) and cycloplegic agents (which block muscarinic receptors in the ciliary body and iris sphincter) cause the iris to bunch up in the iridocorneal angle, precipitating or worsening acute angle-closure glaucoma.

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