Autonomic Nervous System Drugs · NEET PG Preparation Pharmacology
A 28-year-old pregnant female at 34 weeks of gestation presents with preterm labor contractions. To delay delivery and allow for corticosteroid admin…
Practice question from Autonomic Nervous System Drugs (NEET PG Preparation Pharmacology), with the correct answer and a step-by-step solution.
medium · MCQ · Q-47A003
A 28-year-old pregnant female at 34 weeks of gestation presents with preterm labor contractions. To delay delivery and allow for corticosteroid administration, she is given an intravenous drug that acts as a beta-2 adrenergic receptor agonist. Which of the following adverse effects is most commonly observed with this medication?
- A.Hypokalemia and hyperglycemiaCorrect answer
- B.Hyperkalemia and hypoglycemia
- C.Bradycardia and hypothermia
- D.Miosis and skeletal muscle relaxation
Solution
Beta-2 agonists (such as ritodrine or terbutaline) used as tocolytics stimulate glycogenolysis and insulin release, leading to hyperglycemia, and shift potassium intracellularly via the Na+/K+-ATPase pump, causing hypokalemia. Other effects include maternal tachycardia and tremor.
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