Lipid Metabolism · NEET PG Preparation Biochemistry
A 45-year-old man with a family history of premature coronary artery disease is found to have significantly elevated serum LDL cholesterol levels. Ge…
Practice question from Lipid Metabolism (NEET PG Preparation Biochemistry), with the correct answer and a step-by-step solution.
easy · MCQ · Q-5CB8E7
A 45-year-old man with a family history of premature coronary artery disease is found to have significantly elevated serum LDL cholesterol levels. Genetic testing reveals a mutation in the ligand-binding domain of the LDL receptor. Which apolipoprotein on the surface of LDL is normally recognized by this receptor?
- A.Apo A-I
- B.Apo B-48
- C.Apo B-100Correct answer
- D.Apo C-II
Solution
Apo B-100 is the primary apolipoprotein found on LDL (and VLDL) and serves as the specific ligand recognized by the LDL receptor for receptor-mediated endocytosis.
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