Lipid Metabolism · NEET PG Preparation Biochemistry
A newborn infant displays failure to thrive, severe hypoglycemia, and hepatomegaly. Biochemical investigations reveal a deficiency in cytosolic carni…
Practice question from Lipid Metabolism (NEET PG Preparation Biochemistry), with the correct answer and a step-by-step solution.
hard · MCQ · Q-B8F24A
A newborn infant displays failure to thrive, severe hypoglycemia, and hepatomegaly. Biochemical investigations reveal a deficiency in cytosolic carnitine acylcarnitine translocase. This enzyme is crucial for which of the following processes?
- A.Transport of acylcarnitine across the inner mitochondrial membraneCorrect answer
- B.Synthesis of malonyl-CoA in the cytoplasm
- C.Activation of free fatty acids in the cytosol
- D.Reduction of double bonds during unsaturated fatty acid oxidation
Solution
Carnitine acylcarnitine translocase is an antiporter located in the inner mitochondrial membrane that transports acylcarnitine into the mitochondrial matrix in exchange for free carnitine.
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