Cell Injury & Inflammation · NEET PG Preparation Pathology
A 60-year-old smoker dies of a massive stroke. Autopsy examination of the brain reveals an area of liquefactive necrosis in the middle cerebral arter…
Practice question from Cell Injury & Inflammation (NEET PG Preparation Pathology), with the correct answer and a step-by-step solution.
easy · MCQ · Q-813F88
A 60-year-old smoker dies of a massive stroke. Autopsy examination of the brain reveals an area of liquefactive necrosis in the middle cerebral artery territory. Which of the following cells are primarily responsible for the complete digestion and removal of necrotic tissue in the central nervous system?
- A.Astrocytes
- B.Microglia and blood-derived macrophagesCorrect answer
- C.Oligodendrocytes
- D.Neutrophils
Solution
In the central nervous system, liquefactive necrosis occurs due to the lack of substantial solid structural protein matrix. Resident microglia and infiltrating blood-derived macrophages phagocytose the debris, eventually leaving a fluid-filled cystic space.
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